Atopic dermatitis: new insights and opportunities for therapeutic intervention

DYM Leung - Journal of Allergy and Clinical Immunology, 2000 - Elsevier
Atopic dermatitis (AD) is a chronic inflammatory skin disease that frequently predates the
development of allergic rhinitis or asthma. It is an important skin condition with significant
costs and morbidity to patients and their families; the disease affects more than 10% of
children. Recent studies have demonstrated the complex interrelationship of genetic,
environmental, skin barrier, pharmacologic, psychologic, and immunologic factors that
contribute to the development and severity of AD. The current review will examine the …