Decoding calcium signals involved in cardiac growth and function
N Frey, TA McKinsey, EN Olson - Nature medicine, 2000 - nature.com
N Frey, TA McKinsey, EN Olson
Nature medicine, 2000•nature.comCalcium is central in the regulation of cardiac contractility, growth and gene expression.
Variations in the amplitude, frequency and compartmentalization of calcium signals are
decoded by calcium/calmodulin-dependent enzymes, ion channels and transcription factors.
Understanding the circuitry for calcium signaling creates opportunities for pharmacological
modification of cardiac function.
Variations in the amplitude, frequency and compartmentalization of calcium signals are
decoded by calcium/calmodulin-dependent enzymes, ion channels and transcription factors.
Understanding the circuitry for calcium signaling creates opportunities for pharmacological
modification of cardiac function.
Abstract
Calcium is central in the regulation of cardiac contractility, growth and gene expression. Variations in the amplitude, frequency and compartmentalization of calcium signals are decoded by calcium/calmodulin-dependent enzymes, ion channels and transcription factors. Understanding the circuitry for calcium signaling creates opportunities for pharmacological modification of cardiac function.
nature.com