Chloride-dependent amino acid transport in the small intestine: occurrence and significance

LK Munck - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1995 - Elsevier
The concept of sodium-solute cotransport proposed in 1960 by Crane [1, 2] has been
confirmed in numerous studies [3]. Amino acids and sugars are transported across the
mucosal membrane of enterocytes by a secondary active process, driven by the
electrochemical gradient for sodium. The substrates bind to carriers, and transmembrahe
transport is accomplished through a conformational change of the carrier binding sites [3, 4].
Transcellular or vectorial transport is completed by the function of carriers localized in the …