[HTML][HTML] Molecular scanning of the human PPARα gene: association of the L162V mutation with hyperapobetalipoproteinemia
MC Vohl, P Lepage, D Gaudet, CG Brewer… - Journal of lipid …, 2000 - ASBMB
Peroxisome proliferator-activated receptor alpha (PPARα) is a member of the steroid
hormone receptor super family involved in the control of cellular lipid utilization. This makes
PPARα a candidate gene for type 2 diabetes and dyslipidemia. The aim of this study was to
investigate whether genetic variation in the human PPARα gene can influence the risk of
type 2 diabetes and dyslipidemia among French Canadians. We therefore first determined
the genomic structure of human PPARα, and then designed intronic primers to sequence the …
hormone receptor super family involved in the control of cellular lipid utilization. This makes
PPARα a candidate gene for type 2 diabetes and dyslipidemia. The aim of this study was to
investigate whether genetic variation in the human PPARα gene can influence the risk of
type 2 diabetes and dyslipidemia among French Canadians. We therefore first determined
the genomic structure of human PPARα, and then designed intronic primers to sequence the …