Thyroid-pituitary interaction: feedback regulation of thyrotropin secretion by thyroid hormones

PR Larsen - New England Journal of Medicine, 1982 - Mass Medical Soc
New England Journal of Medicine, 1982Mass Medical Soc
Endocrinologists, particularly those with a special interest in thyroid disease, have been
fortunate that several specific and sensitive tests that can establish the diagnosis of thyroid
dysfunction have been developed over the past decade. The three most useful tests are
radioimmunoassays of thyroxine (T4), 3, 5, 3′-triiodothyronine (T3), and thyrotropin, or
thyroid-stimulating hormone (TSH). Clinicians have come to have so much confidence in the
results of these tests that they often question their clinical acumen rather than the validity of a …
Endocrinologists, particularly those with a special interest in thyroid disease, have been fortunate that several specific and sensitive tests that can establish the diagnosis of thyroid dysfunction have been developed over the past decade. The three most useful tests are radioimmunoassays of thyroxine (T4), 3,5,3′-triiodothyronine (T3), and thyrotropin, or thyroid-stimulating hormone (TSH).
Clinicians have come to have so much confidence in the results of these tests that they often question their clinical acumen rather than the validity of a test when the two conflict. Diagnosis in thyroid disorders thus can be difficult not only because of the nonspecificity of symptoms, . . .
The New England Journal Of Medicine