Uptake and metabolism of palmitate by isolated cardiac myocytes from adult rats: involvement of sarcolemmal proteins
JJ Luiken, FA Van Nieuwenhoven, G America… - Journal of lipid …, 1997 - ASBMB
The precise mechanism of uptake of long-chain fatty acids (FA) by cardiac myocytes is
incompletely understood. We examined the involvement of sarcolemmal proteins in the
initial uptake of FA by isolated rat cardiac myocytes, and the relation between initial uptake
and metabolism. Cardiac myocytes were incubated in the presence of 90 microns [1-14C]
palmitate complexed to 300 microns bovine serum albumin (BSA), presenting a
physiologically relevant condition. During initial palmitate uptake (3 min), 56% of the …
incompletely understood. We examined the involvement of sarcolemmal proteins in the
initial uptake of FA by isolated rat cardiac myocytes, and the relation between initial uptake
and metabolism. Cardiac myocytes were incubated in the presence of 90 microns [1-14C]
palmitate complexed to 300 microns bovine serum albumin (BSA), presenting a
physiologically relevant condition. During initial palmitate uptake (3 min), 56% of the …