Role of monoclonal O-antigen antibody epitope specificity and isotype in protection against experimental mouse typhoid
NIA Carlin, SB Svenson, AA Lindberg - Microbial pathogenesis, 1987 - Elsevier
A panel of 14 monoclonal antibodies with specificity for the O-antigenic polysaccharide
chain of the lipopolysaccharide of the cell envelope of Salmonella typhimurium was
established. The specificity of each antibody clone was determined against a set of
Salmonella saccharide antigens, natural and synthetic, in passive hemagglutination and
enzyme immunoassays. The monoclonal antibodies could be classified into at least five
different groups:(i) O4 epitope specific,(ii) O4, 12 specific,(iii) O4, 12 2 specific,(iv) O5 …
chain of the lipopolysaccharide of the cell envelope of Salmonella typhimurium was
established. The specificity of each antibody clone was determined against a set of
Salmonella saccharide antigens, natural and synthetic, in passive hemagglutination and
enzyme immunoassays. The monoclonal antibodies could be classified into at least five
different groups:(i) O4 epitope specific,(ii) O4, 12 specific,(iii) O4, 12 2 specific,(iv) O5 …