The role of neisserial Opa proteins in interactions with host cells
C Dehio, SD Gray-Owen, TF Meyer - Trends in microbiology, 1998 - cell.com
C Dehio, SD Gray-Owen, TF Meyer
Trends in microbiology, 1998•cell.comPathogenic Neisseria spp. possess a repertoire of phase-variable Opa proteins that mediate
various pathogen–host cell interactions, including bacterial engulfment by epithelial cells
and opsonin-independent phagocytosis by professional phagocytes. Recent studies have
identified cellular targets recognized by defined Opa proteins and have begun to reveal host
signalling events involved in mediating these Opa-dependent cellular processes.
various pathogen–host cell interactions, including bacterial engulfment by epithelial cells
and opsonin-independent phagocytosis by professional phagocytes. Recent studies have
identified cellular targets recognized by defined Opa proteins and have begun to reveal host
signalling events involved in mediating these Opa-dependent cellular processes.
Abstract
Pathogenic Neisseria spp. possess a repertoire of phase-variable Opa proteins that mediate various pathogen–host cell interactions, including bacterial engulfment by epithelial cells and opsonin-independent phagocytosis by professional phagocytes. Recent studies have identified cellular targets recognized by defined Opa proteins and have begun to reveal host signalling events involved in mediating these Opa-dependent cellular processes.
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