Hyper-and hypo-responsiveness to dietary fat and cholesterol among inbred mice: searching for level and variability genes
EA Kirk, GL Moe, MT Caldwell, JA Lernmark… - Journal of lipid …, 1995 - ASBMB
A concept proposed by Berg (Berg, K. 1989. Arteriosclerosis. 9: I-50-I-58) is that a
combination of level and variability genes determine an individual's overall plasma lipid
levels and atherosclerotic risk. Our goal was to determine which inbred mouse strains could
be used to identify candidate level and variability genes controlling lipid levels and
atherosclerosis susceptibility. Nine common inbred mouse strains were examined for
responsiveness with respect to plasma lipoprotein and tissue lipid levels upon feeding diets …
combination of level and variability genes determine an individual's overall plasma lipid
levels and atherosclerotic risk. Our goal was to determine which inbred mouse strains could
be used to identify candidate level and variability genes controlling lipid levels and
atherosclerosis susceptibility. Nine common inbred mouse strains were examined for
responsiveness with respect to plasma lipoprotein and tissue lipid levels upon feeding diets …