Circulating elevated levels of soluble CD23, interleukin-4, and CD20+ CD23+ lymphocytes in atopic subjects with elevated serum IgE concentrations.
MM Reddy, AM Weissman, DS Mazza… - Annals of …, 1992 - europepmc.org
MM Reddy, AM Weissman, DS Mazza, DK Meriney, M Johns, S Carrabis, MH Grieco
Annals of allergy, 1992•europepmc.orgCirculating IgE protein levels, leukocyte counts, lymphocyte subsets, IL-4, and soluble CD23
levels were quantitated in 43 atopic and 19 nonatopic subjects. Mean values of IgE protein
levels, total eosinophil counts, CD20+ CD23+ cells (B cells with low-affinity IgE receptor), IL-
4 and sCD23 levels were elevated in atopic patients compared with nonatopic controls. The
results suggest that sCD23, IL-4, and CD20+ CD23+ lymphocytes may play a role in the
increased production of IgE in atopic subjects in a manner similar to that observed by other …
levels were quantitated in 43 atopic and 19 nonatopic subjects. Mean values of IgE protein
levels, total eosinophil counts, CD20+ CD23+ cells (B cells with low-affinity IgE receptor), IL-
4 and sCD23 levels were elevated in atopic patients compared with nonatopic controls. The
results suggest that sCD23, IL-4, and CD20+ CD23+ lymphocytes may play a role in the
increased production of IgE in atopic subjects in a manner similar to that observed by other …
Circulating IgE protein levels, leukocyte counts, lymphocyte subsets, IL-4, and soluble CD23 levels were quantitated in 43 atopic and 19 nonatopic subjects. Mean values of IgE protein levels, total eosinophil counts, CD20+ CD23+ cells (B cells with low-affinity IgE receptor), IL-4 and sCD23 levels were elevated in atopic patients compared with nonatopic controls. The results suggest that sCD23, IL-4, and CD20+ CD23+ lymphocytes may play a role in the increased production of IgE in atopic subjects in a manner similar to that observed by other investigators in prior in vitro studies.
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