Transcriptional regulation and spatial patterning in Drosophila
M Hoch, H Jäckle - Current opinion in genetics & development, 1993 - Elsevier
M Hoch, H Jäckle
Current opinion in genetics & development, 1993•ElsevierPattern formation in Drosophila is initiated by a small set of asymmetrically distributed
maternal transcription factors that act as graded morphogens along the anterior-posterior
and the dorsal-ventral axes of the embryo. Recent progress in the field provides first insight
into the molecular mechanisms by which long-range positional information in the egg
causes a series of localized zygotic transcription factors to position the developmental fate
along the blastoderm.
maternal transcription factors that act as graded morphogens along the anterior-posterior
and the dorsal-ventral axes of the embryo. Recent progress in the field provides first insight
into the molecular mechanisms by which long-range positional information in the egg
causes a series of localized zygotic transcription factors to position the developmental fate
along the blastoderm.
Abstract
Pattern formation in Drosophila is initiated by a small set of asymmetrically distributed maternal transcription factors that act as graded morphogens along the anterior-posterior and the dorsal-ventral axes of the embryo. Recent progress in the field provides first insight into the molecular mechanisms by which long-range positional information in the egg causes a series of localized zygotic transcription factors to position the developmental fate along the blastoderm.
Elsevier