Interactions between enteropathogenic Escherichia coli and host epithelial cells

MS Donnenberg, JB Kaper, BB Finlay - Trends in microbiology, 1997 - cell.com
Trends in microbiology, 1997cell.com
The pathogenesis of enteropathogenic Escherichia coli (EPEC) infection is emerging as a
paradigm for a multistage microorganism-host cell interaction. Both type IV fimbriae and a
type HI secretion apparatus play principal roles in interactions between the bacteria and
host cells. Recent data suggest that bacteria-induced signal transduction activates the
receptor that allows tenacious adherence of the bacteria to the host cell surface.
The pathogenesis of enteropathogenic Escherichia coli (EPEC) infection is emerging as a paradigm for a multistage microorganism-host cell interaction. Both type IV fimbriae and a type HI secretion apparatus play principal roles in interactions between the bacteria and host cells. Recent data suggest that bacteria-induced signal transduction activates the receptor that allows tenacious adherence of the bacteria to the host cell surface.
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