[HTML][HTML] The Drosophila tumor necrosis factor receptor-associated factor-1 (DTRAF1) interacts with Pelle and regulates NFκB activity
A member of the tumor necrosis factor (TNF) receptor-associated factor (TRAF) family was
identified inDrosophila. DTRAF1 contains 7 zinc finger domains followed by a TRAF domain,
similar to mammalian TRAFs and other members of the family identified in data bases from
Caenorhabditis elegans, Arabidopsis, and Dictyostelium. Analysis of DTRAF1 binding to
different members of the human TNF receptor family showed that this protein can interact
through its TRAF domain with the p75 neurotrophin receptor and weakly with the …
identified inDrosophila. DTRAF1 contains 7 zinc finger domains followed by a TRAF domain,
similar to mammalian TRAFs and other members of the family identified in data bases from
Caenorhabditis elegans, Arabidopsis, and Dictyostelium. Analysis of DTRAF1 binding to
different members of the human TNF receptor family showed that this protein can interact
through its TRAF domain with the p75 neurotrophin receptor and weakly with the …