[HTML][HTML] Organization and myogenic restricted expression of the murine serum response factor gene: a role for autoregulation
NS Belaguli, LA Schildmeyer, RJ Schwartz - Journal of Biological Chemistry, 1997 - ASBMB
Serum response factor (SRF), a member of an ancient family of DNA-binding proteins, is
generally assumed to be a ubiquitous transcription factor involved in regulating growth factor-
responsive genes. However, avian SRF was recently shown (Croissant, JD, Kim, J.-H.,
Eichele, G., Goering, L., Lough, J., Prywes, R., and Schwartz, RJ (1996) Dev. Biol. 177, 250–
264) to be preferentially expressed in myogenic lineages and is required for regulating post-
replicative muscle gene expression. Given the central importance of SRF for the muscle …
generally assumed to be a ubiquitous transcription factor involved in regulating growth factor-
responsive genes. However, avian SRF was recently shown (Croissant, JD, Kim, J.-H.,
Eichele, G., Goering, L., Lough, J., Prywes, R., and Schwartz, RJ (1996) Dev. Biol. 177, 250–
264) to be preferentially expressed in myogenic lineages and is required for regulating post-
replicative muscle gene expression. Given the central importance of SRF for the muscle …