Longitudinal and secular trends in lipoprotein cholesterol measurements in a general population sample The Framingham offspring study

KM Anderson, PWF Wilson, RJ Garrison, WP Castelli - Atherosclerosis, 1987 - Elsevier
Two fasting lipoprotein cholesterol measurements have been made on Framingham
Offspring Study participants, first in 1971–1975 and again in 1979–1983. Longitudinal
analysis (n= 2433, age 20–49 at first exam) using multivariate regression found aging,
weight gain, vasectomy, menopause, and increased smoking are associated with worsening
lipoprotein profiles, while increased alcohol consumption is associated with increased high
density lipoprotein cholesterol (HDL-C). Average increases in low density lipoprotein …