[PDF][PDF] RETRACTED: The Fas/Fas Ligand Pathway and Bcl-2 Regulate T Cell Responses to Model Self and Foreign Antigens

L Van Parijs, DA Peterson, AK Abbas - Immunity, 1998 - cell.com
L Van Parijs, DA Peterson, AK Abbas
Immunity, 1998cell.com
The Fas/Fas Ligand Pathway and Bcl-2 Regulate T Cell Responses to Model Self and
Foreign Antigens Page 1 Immunity, Vol. 8, 265–274, February, 1998, Copyright ©1998 by Cell
Press The Fas/Fas Ligand Pathway and Bcl-2 Regulate T Cell Responses to Model Self and
Foreign Antigens molecules that function to limit T cell responses by inducing T cell anergy or
apoptosis lead to autoimmune diseases that are often lethal (Singer and Abbas, 1994;
Nagata and Suda, 1995; Tivol et al., 1996). Despite many recent advances, the mechanisms …
Summary
The best-defined regulators of T cell apoptosis are Fas and related proteins of the tumor necrosis factor
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