C1q receptors: regulating specific functions of phagocytic cells
AJ Tenner - Immunobiology, 1998 - Elsevier
A C1q receptor that upregulates the phagocytec capacity of professional phagocytes,
C1qRP, has been identified, and its primary structure determined by cDNA cloning and
sequencing. Monoclonal antibodies that immunoprecipitate this 126,000 Mr polypeptide
inhibit the enhancement of phagocytosis triggered not only by C1q but also by mannose
binding lectin (MBL) and pulmonary surfactant protein A (SPA) providing critical evidence
that this polypeptide is a functional receptor or component of the receptor that mediates this …
C1qRP, has been identified, and its primary structure determined by cDNA cloning and
sequencing. Monoclonal antibodies that immunoprecipitate this 126,000 Mr polypeptide
inhibit the enhancement of phagocytosis triggered not only by C1q but also by mannose
binding lectin (MBL) and pulmonary surfactant protein A (SPA) providing critical evidence
that this polypeptide is a functional receptor or component of the receptor that mediates this …