The multiple murine 3β-hydroxysteroid dehydrogenase isoforms: structure, function, and tissue-and developmentally specific expression
AH Payne, IG Abbaszade, TR Clarke, PA Bain… - Steroids, 1997 - Elsevier
The enzyme 3β-hydroxysteroid dehydrogenase (3β-HSD) is essential for the biosynthesis of
all active steroid hormones. To date five distinct isoforms have been identified in the mouse.
The different isoforms are indicated by roman numerals (I–V) in the chronological order in
which they have been isolated. The different isoforms are expressed in a tissue-and
developmentally specific manner and fall into two functionally distinct groups. 3β-HSD I, II,
and III function as NAD+-dependent dehydrogenase/isomerases, and IV and V function as …
all active steroid hormones. To date five distinct isoforms have been identified in the mouse.
The different isoforms are indicated by roman numerals (I–V) in the chronological order in
which they have been isolated. The different isoforms are expressed in a tissue-and
developmentally specific manner and fall into two functionally distinct groups. 3β-HSD I, II,
and III function as NAD+-dependent dehydrogenase/isomerases, and IV and V function as …