Immunobiology of primary intracranial tumors: Part 1: studies of the cellular and humoral general immune competence of brain-tumor patients
MS Mahaley, WH Brooks, TL Roszman… - Journal of …, 1977 - thejns.org
MS Mahaley, WH Brooks, TL Roszman, DD Bigner, L Dudka, S Richardson
Journal of neurosurgery, 1977•thejns.org✓ Cellular and humoral immune parameters were evaluated in a series of braintumor
patients, 42 with glioblastoma multiforme, 17 with other anaplastic gliomas, and 17 with
meningiomas. A degree of anergy was found, which seems in the group as a whole to be
proportional to the degree of anaplasia. In addition, serial bimonthly testing in individual
cases revealed further reduction in certain immune responses coincident with clinical
decline.
patients, 42 with glioblastoma multiforme, 17 with other anaplastic gliomas, and 17 with
meningiomas. A degree of anergy was found, which seems in the group as a whole to be
proportional to the degree of anaplasia. In addition, serial bimonthly testing in individual
cases revealed further reduction in certain immune responses coincident with clinical
decline.
✓ Cellular and humoral immune parameters were evaluated in a series of braintumor patients, 42 with glioblastoma multiforme, 17 with other anaplastic gliomas, and 17 with meningiomas. A degree of anergy was found, which seems in the group as a whole to be proportional to the degree of anaplasia. In addition, serial bimonthly testing in individual cases revealed further reduction in certain immune responses coincident with clinical decline.
thejns.org