Immunological modulation and evasion by helminth parasites in human populations

RM Maizels, DAP Bundy, ME Selkirk, DF Smith… - Nature, 1993 - nature.com
Nature, 1993nature.com
Helminth parasites are highly prevalent in human communities in developing countries. In
an endemic area an infected individual may harbour parasitic worms for most of his or her
life, and the ability of these infections to survive immunological attack has long been a
puzzle. But new techniques are starting to expose the diverse mechanisms by which these
agents modulate or evade their hosts' defences, creating a dynamic interaction between the
human immune system and the parasite population.
Abstract
Helminth parasites are highly prevalent in human communities in developing countries. In an endemic area an infected individual may harbour parasitic worms for most of his or her life, and the ability of these infections to survive immunological attack has long been a puzzle. But new techniques are starting to expose the diverse mechanisms by which these agents modulate or evade their hosts' defences, creating a dynamic interaction between the human immune system and the parasite population.
nature.com