The temporal evolution of MRI tissue signatures after transient middle cerebral artery occlusion in rat

Q Jiang, M Chopp, ZG Zhang, RA Knight… - Journal of the …, 1997 - Elsevier
We have developed a multiparameter magnetic resonance imaging (MRI) cluster analysis
model of acute ischemic stroke using T2 relaxation times and the diffusion coefficient of
water (ADCw). To test the ability of this model to predict cerebral infarction, male Wistar rats
(n= 7) were subjected to 2 h of transient middle cerebral artery (MCA) occlusion, and
diffusion and T2 weighted MRI were performed on these rats before, during and up to 7 days
after MCA occlusion. MRI tissue signatures, specified by values of ADCw and T2 were …