[HTML][HTML] Identification and Molecular Cloning of a Human Selenocysteine Insertion Sequence-binding Protein: A BIFUNCTIONAL ROLE FOR DNA-BINDING PROTEIN …
Q Shen, R Wu, JL Leonard, PE Newburger - Journal of Biological Chemistry, 1998 - ASBMB
Prokaryotic and eukaryotic cells incorporate the unusual amino acid selenocysteine at a
UGA codon, which conventionally serves as a termination signal. Translation of eukaryotic
selenoprotein mRNA requires a nucleotide selenocysteine insertion sequence in the 3′-
untranslated region. We report the molecular cloning of the binding protein that recognizes
the selenocysteine insertion sequence element in human cellular glutathione peroxidase
gene (GPX1) transcripts and its identification as DNA-binding protein B, a member of the EFI …
UGA codon, which conventionally serves as a termination signal. Translation of eukaryotic
selenoprotein mRNA requires a nucleotide selenocysteine insertion sequence in the 3′-
untranslated region. We report the molecular cloning of the binding protein that recognizes
the selenocysteine insertion sequence element in human cellular glutathione peroxidase
gene (GPX1) transcripts and its identification as DNA-binding protein B, a member of the EFI …