[PDF][PDF] Effects of Insulin and Acipimox on VLDL1 and VLDL2Apolipoprotein B Production in Normal

R Malmstrım, CJ Packard, M Caslake, D Bedford… - Diabetes, 1998 - researchgate.net
The objective of the study was to examine the potential differential effect of insulin and
acipimox (both of which reduce free fatty acid [FFA] availability) on VLDL apolipoprotein
(apo) B metabolism. We studied eight healthy men (age 40 e 4 years, BMI 25.8* 0.9 kg/m “,
plasma triglycerides 1.30= 0.12 mmol/l) after an overnight fast (control study, n= 8), during
inhibition of lipolysis with an antilipolytic agent, acipimox (n.= 8), and under 8.5-h
euglycemic-hyperinsulinemic con-ditions (n= 5). Plasma FFAs were similarly suppressed in …