Evaluation of ventricular and arterial hemodynamics in anesthetized closed-chest mice
RC Fentzke, CE Korcarz, SG Shroff, H Lin… - Journal of the American …, 1997 - Elsevier
Transgenic and knock-out mice with cardiovascular phenotypes have created the need for
methods to measure murine arterial and ventricular mechanics. The aims of this study were
(1) to develop a method for the assessment of wall stress (σes)-rate corrected velocity of
fiber shortening (Vcfc) relation and (2) to assess the feasibility of quantifying global arterial
function in normal mice. This method can thus serve as a reference for future studies in
genetically altered mice by establishing normal values for comparison. Ten anesthetized …
methods to measure murine arterial and ventricular mechanics. The aims of this study were
(1) to develop a method for the assessment of wall stress (σes)-rate corrected velocity of
fiber shortening (Vcfc) relation and (2) to assess the feasibility of quantifying global arterial
function in normal mice. This method can thus serve as a reference for future studies in
genetically altered mice by establishing normal values for comparison. Ten anesthetized …