[HTML][HTML] Molecular identification of a putative human hyaluronan synthase

K Watanabe, Y Yamaguchi - Journal of Biological Chemistry, 1996 - ASBMB
To identify the putative mammalian hyaluronan synthase, we cloned a human cDNA that is
related to the Streptococcus hyaluronan synthase (HasA) and the Xenopus developmental
protein DG42 which has been shown to have chitin synthase activity. The cDNA, for which
we propose the name Has2, encodes a novel protein with a predicted molecular mass of
63.6 kDa. Has2 shows 55% amino acid identity with Xenopus DG42 and 52% identity with
the mouse HAS protein, another putative hyaluronan synthase recently reported by Itano …