[CITATION][C] An approach to the prediction of diabetes mellitus by modification of the glucose tolerance test with cortisone
SS Fajans, JW Conn - Diabetes, 1954 - Am Diabetes Assoc
SS Fajans, JW Conn
Diabetes, 1954•Am Diabetes AssocA large proportion of presently nondiabetic individuals who have a family history of diabetes
mellitus will eventually manifest the disease. If one could separate those who harbor the
potentiality for diabetes from those who do not, further study of inciting factors would be
possible. It is conceivable that impairment of reserve isletcell function may exist in such
individuals even though carbohydrate tolerance can be demonstrated to be normal at the
present time. The present study was begun in 1950 with the following objectives: to attempt …
mellitus will eventually manifest the disease. If one could separate those who harbor the
potentiality for diabetes from those who do not, further study of inciting factors would be
possible. It is conceivable that impairment of reserve isletcell function may exist in such
individuals even though carbohydrate tolerance can be demonstrated to be normal at the
present time. The present study was begun in 1950 with the following objectives: to attempt …
A large proportion of presently nondiabetic individuals who have a family history of diabetes mellitus will eventually manifest the disease. If one could separate those who harbor the potentiality for diabetes from those who do not, further study of inciting factors would be possible. It is conceivable that impairment of reserve isletcell function may exist in such individuals even though carbohydrate tolerance can be demonstrated to be normal at the present time.
The present study was begun in 1950 with the following objectives: to attempt to unmask the potential diabetic who manifests normal carbohydrate tolerance by present testing methods; and to determine whether or not the established diabetogenic activity of corticotropin and/or cortisone could be used to bring to the surface a subclinical defect in the metabolism of carbohydrate.
Am Diabetes Assoc