Thyroid function and vitamin A deficiency
JE Morley, DA Damassa, J Gordon, AE Pekary… - Life Sciences, 1978 - Elsevier
JE Morley, DA Damassa, J Gordon, AE Pekary, JM Hershman
Life Sciences, 1978•ElsevierRats, when vitamin A deficient, had increased plasma T 3, T 4 and free thyroxine indexes.
Pituitary TSH and hypothalamic TRH content were increased in vitamin A deficient animals
compared to pair-fed controls. The plasma TSH response to TRH was normal in the vitamin
A deficient rats. Basal prolactin, LH and FSH levels did not differ significantly in the two
groups. Both groups had significant increases in LH and FSH after LRH. Vitamin A
deficiency produces biochemical hyperthyroidism. Our data are consistent with an …
Pituitary TSH and hypothalamic TRH content were increased in vitamin A deficient animals
compared to pair-fed controls. The plasma TSH response to TRH was normal in the vitamin
A deficient rats. Basal prolactin, LH and FSH levels did not differ significantly in the two
groups. Both groups had significant increases in LH and FSH after LRH. Vitamin A
deficiency produces biochemical hyperthyroidism. Our data are consistent with an …
Abstract
Rats, when vitamin A deficient, had increased plasma T3, T4 and free thyroxine indexes. Pituitary TSH and hypothalamic TRH content were increased in vitamin A deficient animals compared to pair-fed controls. The plasma TSH response to TRH was normal in the vitamin A deficient rats. Basal prolactin, LH and FSH levels did not differ significantly in the two groups. Both groups had significant increases in LH and FSH after LRH. Vitamin A deficiency produces biochemical hyperthyroidism. Our data are consistent with an abnormality in thyroid hormone feedback on the hypothalamic pituitary axis.
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