Chimerism and transplantation tolerance: cause and effect

K Wood, DH Sachs - Immunology Today, 1996 - elibrary.ru
K Wood, DH Sachs
Immunology Today, 1996elibrary.ru
Evidence for persistence of donor leukocytes in recipients of long-term organ allografts has
prompted the hypothesis that such microchimerism is not only essential to graft survival but
that donor and host cells both play active roles. Here, Kathryn Wood and David Sachs
caution that the jury is still out on whether such microchimerism is the cause or merely the
consequence of long-term allografting.
Аннотация
Evidence for persistence of donor leukocytes in recipients of long-term organ allografts has prompted the hypothesis that such microchimerism is not only essential to graft survival but that donor and host cells both play active roles. Here, Kathryn Wood and David Sachs caution that the jury is still out on whether such microchimerism is the cause or merely the consequence of long-term allografting.
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