Transplantation of isolated pancreatic islets into the portal vein of diabetic rats
CB Kemp, MJ Knight, DW Scharp, PE Lacy… - Nature, 1973 - nature.com
CB Kemp, MJ Knight, DW Scharp, PE Lacy, WF Ballinger
Nature, 1973•nature.comRECENT work from this laboratory indicates that intraperitoneal transplantation of isolated
pancreatic islets ameliorates the effects of experimental diabetes in rats1. Although the
intraperitoneal siting of these islets reduces the hyperglycaemia and polyuria of
streptozotocin induced diabetes in these animals, consistently normal values for blood sugar
and urine volume are rarely achieved.
pancreatic islets ameliorates the effects of experimental diabetes in rats1. Although the
intraperitoneal siting of these islets reduces the hyperglycaemia and polyuria of
streptozotocin induced diabetes in these animals, consistently normal values for blood sugar
and urine volume are rarely achieved.
Abstract
RECENT work from this laboratory indicates that intraperitoneal transplantation of isolated pancreatic islets ameliorates the effects of experimental diabetes in rats1. Although the intraperitoneal siting of these islets reduces the hyperglycaemia and polyuria of streptozotocin induced diabetes in these animals, consistently normal values for blood sugar and urine volume are rarely achieved.
nature.com