The erosive front: a topographic study of the junction between the pannus and the subchondral plate in the macerated rheumatoid metacarpal head.
JC Leisen, H Duncan, JM Riddle… - The Journal of …, 1988 - europepmc.org
JC Leisen, H Duncan, JM Riddle, WC Pitchford
The Journal of rheumatology, 1988•europepmc.orgThe junction between cellular pannus and cartilage/bone was identified grossly on
rheumatoid metacarpal heads. Its topography was displayed by scanning electron
microscopy using macerated samples. A uniform pattern of resorption bays, typical of
osteoclastic activity, was seen spreading over the surfaces of both calcified cartilage and
subchondral bone. The contact area between pannus and cartilage/bone was found to
represent an erosive front. Morphologic evidence suggested that osteoclasts were primarily …
rheumatoid metacarpal heads. Its topography was displayed by scanning electron
microscopy using macerated samples. A uniform pattern of resorption bays, typical of
osteoclastic activity, was seen spreading over the surfaces of both calcified cartilage and
subchondral bone. The contact area between pannus and cartilage/bone was found to
represent an erosive front. Morphologic evidence suggested that osteoclasts were primarily …
The junction between cellular pannus and cartilage/bone was identified grossly on rheumatoid metacarpal heads. Its topography was displayed by scanning electron microscopy using macerated samples. A uniform pattern of resorption bays, typical of osteoclastic activity, was seen spreading over the surfaces of both calcified cartilage and subchondral bone. The contact area between pannus and cartilage/bone was found to represent an erosive front. Morphologic evidence suggested that osteoclasts were primarily responsible for the destructive process.
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