[PDF][PDF] Antigen-presenting cells: professionals and amateurs

J Sprent - Current Biology, 1995 - cell.com
Current Biology, 1995cell.com
Professionals and amateurs Page 1 JONATHAN SPRENT ANTIGEN-PRESENTING CELLS
Professionals and amateurs Professional antigen-presenting cells, notably dendritic cells, play
a key role in stimulating naive T cells - but nonprofessional antigenpresenting cells, such as
fibroblasts, may also contribute to this process. Stimulation of mature T cells generally requires
the presence of specialized antigen-presenting cells, such as macrophages and dendritic
cells [1-6]. These cells are strategically positioned in the T-cell-dependent areas of lymphoid …
Abstract
Professional antigen-presenting cells, notably dendritic cells, play a key role in stimulating naive T cells — but nonprofessional antigen-presenting cells, such as fibroblasts, may also contribute to this process.
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