Vascular angiotensin-converting enzyme activity in cholesterol-fed rabbits: effects of enalapril
S Hoshida, M Nishida, N Yamashita, J Igarashi, K Aoki… - Atherosclerosis, 1997 - Elsevier
Many reports have shown inhibitory effects of angiotensin-converting enzyme (ACE)
inhibitors on the progression of atherosclerotic plaque lesions in vascular tissue of
experimental models. However, no report has shown alterations of ACE activity in vascular
tissue during the process of atherosclerosis. We measured ACE activity in plasma and aortic
tissue in rabbits fed a cholesterol-rich (1%) or normal diet for 10 weeks. We also evaluated
the blood pressure response to angiotensin (Ang) I and II. These data were compared in …
inhibitors on the progression of atherosclerotic plaque lesions in vascular tissue of
experimental models. However, no report has shown alterations of ACE activity in vascular
tissue during the process of atherosclerosis. We measured ACE activity in plasma and aortic
tissue in rabbits fed a cholesterol-rich (1%) or normal diet for 10 weeks. We also evaluated
the blood pressure response to angiotensin (Ang) I and II. These data were compared in …