The clinical course of multiple sclerosis during pregnancy and the puerperium
K Birk, C Ford, S Smeltzer, D Ryan, R Miller… - Archives of …, 1990 - jamanetwork.com
• Eight women with multiple sclerosis were followed up through pregnancy. Clinical
conditions, T-cell subsets, and levels of immunoactive pregnancy-associated proteins were
measured twice during the pregnancy and twice during the first postpartum year. None of the
women's conditions worsened during pregnancy, although one woman reported a slight
increase of symptoms. Six of the eight women experienced relapses within the first 7 weeks
after delivery. The number and percent of CD8 suppressor T cells were lower, and the CD4 …
conditions, T-cell subsets, and levels of immunoactive pregnancy-associated proteins were
measured twice during the pregnancy and twice during the first postpartum year. None of the
women's conditions worsened during pregnancy, although one woman reported a slight
increase of symptoms. Six of the eight women experienced relapses within the first 7 weeks
after delivery. The number and percent of CD8 suppressor T cells were lower, and the CD4 …