[HTML][HTML] Metalloprotease-disintegrins: links to cell adhesion and cleavage of TNFα and Notch

CP Blobel - Cell, 1997 - cell.com
CP Blobel
Cell, 1997cell.com
In the short history of the field of metalloprotease-disintegrin proteins, several fascinating
and remarkably different paths of inquiry have converged on the discovery of new members
of this protein family. About eight years ago, purification of a potent anticoagulant toxin and
high-affinity integrin ligand from snake venom yielded the first sequence of a soluble
disintegrin protein (
In the short history of the field of metalloprotease-disintegrin proteins, several fascinating and remarkably different paths of inquiry have converged on the discovery of new members of this protein family. About eight years ago, purification of a potent anticoagulant toxin and high-affinity integrin ligand from snake venom yielded the first sequence of a soluble disintegrin protein (
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