Regulation of ACTH secretion: variations on a theme of B

MF DALLMAN, SF AKANA, CS CASCIO… - Proceedings of the 1986 …, 1987 - Elsevier
Publisher Summary This chapter discusses the regulation of function in the adrenocortical
system. There are three major characteristics that describe most changes in activity of the
system:(1) the circadian rhythm in basal activity,(2) stress-induced activation, and (3)
corticosteroid feedback regulation. The first two may occur on very different timescales, and
it is probably a consequence of the differing temporal demands that the third, corticosteroid
feedback inhibition, is exerted by a variety of mechanisms over time. At any time of the day …