[HTML][HTML] Identification of a form of acyl-CoA: cholesterol acyltransferase specific to liver and intestine in nonhuman primates
RA Anderson, C Joyce, M Davis, JW Reagan… - Journal of Biological …, 1998 - ASBMB
The present study demonstrates that two different forms of the intracellular cholesterol
esterification enzyme acyl-CoA: cholesterol acyltransferase (ACAT) are present in the
nonhuman primate hepatocyte; one is similar to that originally cloned from human genomic
DNA, here termed ACAT1, while a second gene product, termed ACAT2, is reported here.
The primate ACAT2 gene product was cloned from an African green monkey liver cDNA
library. Sequence analysis of an isolated, full-length clone of ACAT2 cDNA identified an …
esterification enzyme acyl-CoA: cholesterol acyltransferase (ACAT) are present in the
nonhuman primate hepatocyte; one is similar to that originally cloned from human genomic
DNA, here termed ACAT1, while a second gene product, termed ACAT2, is reported here.
The primate ACAT2 gene product was cloned from an African green monkey liver cDNA
library. Sequence analysis of an isolated, full-length clone of ACAT2 cDNA identified an …