Transgenes in autoimmunity
MS Lee, N Sarvetnick - Current opinion in immunology, 1992 - Elsevier
MS Lee, N Sarvetnick
Current opinion in immunology, 1992•ElsevierThe ability of transgenic mice to express a specific protein in a specific tissue has enabled
the mechanisms of self-tolerance and autoimmunity to be elucidated. Further studies,
combined with more sophisticated methods of gene targeting, will provide insights into the
pathway leading from loss of self-tolerance to autoimmunity.
the mechanisms of self-tolerance and autoimmunity to be elucidated. Further studies,
combined with more sophisticated methods of gene targeting, will provide insights into the
pathway leading from loss of self-tolerance to autoimmunity.
Abstract
The ability of transgenic mice to express a specific protein in a specific tissue has enabled the mechanisms of self-tolerance and autoimmunity to be elucidated. Further studies, combined with more sophisticated methods of gene targeting, will provide insights into the pathway leading from loss of self-tolerance to autoimmunity.
Elsevier