Epidermal lipids, barrier function, and desquamation.
PM Elias - Journal of Investigative Dermatology, 1983 - search.ebscohost.com
PM Elias
Journal of Investigative Dermatology, 1983•search.ebscohost.comBased on recent morphologic, histochemical, and biochemical data, we propose a
heterogeneous two-compartment model of the stratum corneum that ascribes a special role
for intercellular lipids in the regulation of stratum corneum barrier function and
desquamation. The evidence in favor of the model and several predictions based on the
model are surveyed in this review.
heterogeneous two-compartment model of the stratum corneum that ascribes a special role
for intercellular lipids in the regulation of stratum corneum barrier function and
desquamation. The evidence in favor of the model and several predictions based on the
model are surveyed in this review.
Abstract
Based on recent morphologic, histochemical, and biochemical data, we propose a heterogeneous two-compartment model of the stratum corneum that ascribes a special role for intercellular lipids in the regulation of stratum corneum barrier function and desquamation. The evidence in favor of the model and several predictions based on the model are surveyed in this review.
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