Mouse angiotensin receptor genes Agtrla and Agtr1b map to Chromosomes 13 and 3
TE MacTaggart, M Ito, O Smithies… - Mammalian …, 1997 - search.proquest.com
TE MacTaggart, M Ito, O Smithies, SWM John
Mammalian genome, 1997•search.proquest.comDiscussion: The renin-angiotensin system plays a primary role in cardiovascular
homeostasis. Many of the biological effects of this system are mediated by the octapeptide
angiotensin II, which interacts with specific cell surface receptors [5]. There are two
pharmacologically distinct types of angiotensin II receptors, designated type 1 (AT1) and
type II (AT2). Two subtypes of type I receptor have been identified in rodents (ATla and
ATlb)[6, 7]. ATla and
homeostasis. Many of the biological effects of this system are mediated by the octapeptide
angiotensin II, which interacts with specific cell surface receptors [5]. There are two
pharmacologically distinct types of angiotensin II receptors, designated type 1 (AT1) and
type II (AT2). Two subtypes of type I receptor have been identified in rodents (ATla and
ATlb)[6, 7]. ATla and
Discussion: The renin-angiotensin system plays a primary role in cardiovascular homeostasis. Many of the biological effects of this system are mediated by the octapeptide angiotensin II, which interacts with specific cell surface receptors [5]. There are two pharmacologically distinct types of angiotensin II receptors, designated type 1 (AT1) and type II (AT2). Two subtypes of type I receptor have been identified in rodents (ATla and ATlb)[6, 7]. ATla and
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