Endocrine pancreas: three-dimensional reconstruction shows two types of islets of langerhans
D Baetens, F Malaisse-Lagae, A Perrelet, L Orci - Science, 1979 - science.org
D Baetens, F Malaisse-Lagae, A Perrelet, L Orci
Science, 1979•science.orgThree-dimensional reconstructions of islets of Langerhans, based on immunofluorescent
staining of successive serial sections with antiserums to insulin, glucagon, somatostatin, and
pancreatic polypeptide reveal a marked difference in the number of cells containing
glucagon and pancreatic polypeptide depending on the anatomical location of the islet in
the pancreas. The two types of islets are situated in regions of exocrine tissue that are
drained by different excretory ducts. This demonstration contradicts the assumption that all …
staining of successive serial sections with antiserums to insulin, glucagon, somatostatin, and
pancreatic polypeptide reveal a marked difference in the number of cells containing
glucagon and pancreatic polypeptide depending on the anatomical location of the islet in
the pancreas. The two types of islets are situated in regions of exocrine tissue that are
drained by different excretory ducts. This demonstration contradicts the assumption that all …
Three-dimensional reconstructions of islets of Langerhans, based on immunofluorescent staining of successive serial sections with antiserums to insulin, glucagon, somatostatin, and pancreatic polypeptide reveal a marked difference in the number of cells containing glucagon and pancreatic polypeptide depending on the anatomical location of the islet in the pancreas. The two types of islets are situated in regions of exocrine tissue that are drained by different excretory ducts. This demonstration contradicts the assumption that all islets in the pancreas are similar in their endocrine cell content.
AAAS