Cbfa1 in bone development
T Komori, T Kishimoto - Current opinion in genetics & development, 1998 - Elsevier
T Komori, T Kishimoto
Current opinion in genetics & development, 1998•ElsevierA factor fundamental to bone formation has been identified. Gene targeting shows that core-
binding factor α1 (Cbfa1) plays an essential role in bone formation and osteoblast
differentiation. Thus, it is now possible to begin examining the molecular mechanisms of
bone formation—especially osteoblast differentiation.
binding factor α1 (Cbfa1) plays an essential role in bone formation and osteoblast
differentiation. Thus, it is now possible to begin examining the molecular mechanisms of
bone formation—especially osteoblast differentiation.
A factor fundamental to bone formation has been identified. Gene targeting shows that core-binding factor α1 (Cbfa1) plays an essential role in bone formation and osteoblast differentiation. Thus, it is now possible to begin examining the molecular mechanisms of bone formation — especially osteoblast differentiation.
Elsevier