[CITATION][C] Mutation in hepatocyte nuclear factor–1β gene (TCF2) associated with MODY
Y Horikawa, N Iwasaki, M Hara, H Furuta, Y Hinokio… - Nature …, 1997 - nature.com
Untitled Page 1 Page 2 © 1997 Nature Publishing Group http://www.nature.com/naturegenetics
sponding reduction in expression of HNF-1 J3 target genes. No mutations were found on
screening of exons 1-4 and flanking introns of the DCoH gene11 in the 57 Japanese subjects
with MODY described above. There was, however, an A~G polymorphism located in the 3'
untranslated region (Table 1), whose frequency was no different between MODY and
non-diabetic subjects. Thus, mutations in DCoH do not appear to contribute to the development …
sponding reduction in expression of HNF-1 J3 target genes. No mutations were found on
screening of exons 1-4 and flanking introns of the DCoH gene11 in the 57 Japanese subjects
with MODY described above. There was, however, an A~G polymorphism located in the 3'
untranslated region (Table 1), whose frequency was no different between MODY and
non-diabetic subjects. Thus, mutations in DCoH do not appear to contribute to the development …