Congenital heart disease results from genetic defects that are manifested at early stages of
embryogenesis. The mouse is the preferred animal model for studies of mammalian
embryonic development and for an increasing number of human disease models. A number
of genes identified in the mouse are critical for normal cardiovascular development, but an
understanding of the underlying mechanisms regulating heart development is still
incomplete, in part because of the lack of methods to measure hemodynamics in live mouse …