[HTML][HTML] Chemokine receptors in human endothelial cells: functional expression of CXCR4 and its transcriptional regulation by inflammatory cytokines
SK Gupta, PG Lysko, K Pillarisetti, E Ohlstein… - Journal of Biological …, 1998 - ASBMB
Chemokines play an important role in the regulation of endothelial cell (EC) function,
including proliferation, migration and differentiation during angiogenesis, and re-
endothelialization after injury. In this study, reverse transcriptase-polymerase chain reaction
was used to reveal expression of various CXC and CC chemokine receptors in human
umbilical vein EC. Northern analysis showed that CXCR4 was selectively expressed in
vascular EC, but not in smooth muscle cells. Compared with other chemokines, stromal cell …
including proliferation, migration and differentiation during angiogenesis, and re-
endothelialization after injury. In this study, reverse transcriptase-polymerase chain reaction
was used to reveal expression of various CXC and CC chemokine receptors in human
umbilical vein EC. Northern analysis showed that CXCR4 was selectively expressed in
vascular EC, but not in smooth muscle cells. Compared with other chemokines, stromal cell …