Expression of intercellular adhesion molecule-1 on rat vascular smooth muscle cells by pro-inflammatory cytokines
U Ikeda, M Ikeda, Y Seino, M Takahashi, T Kasahara… - Atherosclerosis, 1993 - Elsevier
Infiltration of mononuclear cells is an early pathological finding in human and experimental
atherosclerosis. However, the cellular and molecular basis for cell infiltration is incompletely
understood. While the intercellular adhesion molecule-1 (ICAM-1) is expressed on
endothelial cells and promotes the adhesion of mononuclear cells, there is little information
on the expression of ICAM-1 on vascular smooth muscle cells (SMC). In this study, we
investigated the expression of ICAM-1 on cultured rat SMC and its regulation by pro …
atherosclerosis. However, the cellular and molecular basis for cell infiltration is incompletely
understood. While the intercellular adhesion molecule-1 (ICAM-1) is expressed on
endothelial cells and promotes the adhesion of mononuclear cells, there is little information
on the expression of ICAM-1 on vascular smooth muscle cells (SMC). In this study, we
investigated the expression of ICAM-1 on cultured rat SMC and its regulation by pro …