Adenoviral vectors for gene transfer
I Kovesdi, DE Brough, JT Bruder, TJ Wickham - Current opinion in …, 1997 - Elsevier
I Kovesdi, DE Brough, JT Bruder, TJ Wickham
Current opinion in biotechnology, 1997•ElsevierAdenoviruses began to be developed into highly effective gene expression vectors in the
early 1980s. Recently, the increased interest in utilizing this transfer system in vivo has
posed new problems for heterologous gene-transfer, spurring a renewed effort in the field of
vector development toward solving the structural, immunological and targeting problems
posed by gene therapy applications.
early 1980s. Recently, the increased interest in utilizing this transfer system in vivo has
posed new problems for heterologous gene-transfer, spurring a renewed effort in the field of
vector development toward solving the structural, immunological and targeting problems
posed by gene therapy applications.
Adenoviruses began to be developed into highly effective gene expression vectors in the early 1980s. Recently, the increased interest in utilizing this transfer system in vivo has posed new problems for heterologous gene-transfer, spurring a renewed effort in the field of vector development toward solving the structural, immunological and targeting problems posed by gene therapy applications.
Elsevier