CD4 T-lymphocyte activation is associated with peak expiratory flow variability in childhood asthma
S Doi, N Murayama, T Inoue, I Takamatsu… - Journal of allergy and …, 1996 - Elsevier
Background: Asthma has been recognized as a chronic inflammatory disorder of the airway.
We have investigated the relationships among the activation markers on lymphocytes,
eosinophils, their serum products in the peripheral blood, and the variability of airway
obstruction in childhood asthma. Methods: Twenty-two patients with atopic asthma (mean
age, 12 years) were treated regularly and asked to measure their peak expiratory flow (PEF)
twice daily for 7 days. Peripheral venous blood was obtained on day 8. Results: The …
We have investigated the relationships among the activation markers on lymphocytes,
eosinophils, their serum products in the peripheral blood, and the variability of airway
obstruction in childhood asthma. Methods: Twenty-two patients with atopic asthma (mean
age, 12 years) were treated regularly and asked to measure their peak expiratory flow (PEF)
twice daily for 7 days. Peripheral venous blood was obtained on day 8. Results: The …