The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome
J Pugin, G Verghese, MC Widmer… - Critical care …, 1999 - journals.lww.com
Objectives To determine the concentrations of proinflammatory mediators, collagenases,
and procollagen type III peptides in undiluted pulmonary edema fluids and in plasma
obtained in patients with early acute respiratory distress syndrome (ARDS) and in control
patients with hydrostatic lung edema; and to assess the relationship between these
inflammatory and profibrotic markers. Design A prospective, clinical study with
measurements of inflammatory markers in pulmonary edema fluids and in paired plasma …
and procollagen type III peptides in undiluted pulmonary edema fluids and in plasma
obtained in patients with early acute respiratory distress syndrome (ARDS) and in control
patients with hydrostatic lung edema; and to assess the relationship between these
inflammatory and profibrotic markers. Design A prospective, clinical study with
measurements of inflammatory markers in pulmonary edema fluids and in paired plasma …