Subependymal giant cell astrocytoma: a clinical, pathological, and flow cytometric study

CW Shepherd, BW Scheithauer, MR Gomez… - …, 1991 - journals.lww.com
Of 345 patients with tuberous sclerosis complex evaluated at the Mayo Clinic from 1950 to
1989, 23 were identified as having brain tumors. In 20 of the 23, histological or clinical
evidence showed the tumor to be a subependymal giant cell astrocytoma. A search of the
Mayo Clinic tissue registry yielded 73 giant cell-containing astrocytomas and intraventricular
gliomas exclusive of ependymomas. Reexamination revealed no further examples of
subependymal giant cell astrocytoma in patients without features of the tuberous sclerosis …