The selectivity of isoprinosine, NPT 15392, avridine and cyclophosphamide on multiple immune responses in rats
JH Exon, GM Henningsen, LD Koller - International journal of …, 1986 - Elsevier
Multiple concomitant immune responses were assessed in individual rats following
treatment with the immunoenhancing drugs, isoprinosine (5 or 50 mg/kg), NPT 15392 (0.1 or
1.0 mg/kg) and avridine (1 or 25 mg/kg), or the immunosuppressant, cyclophosphamide (75
mg/kg). Immune responses assessed in each rat were specific antibody synthesis, delayed-
type hypersensitivity (DTH), natural killer cell (NKC) cytoxicity and production of three
immunoregulatory cytokines, interleukin 1 (IL1), interleukin 2 (IL2) and prostaglandin E 2 …
treatment with the immunoenhancing drugs, isoprinosine (5 or 50 mg/kg), NPT 15392 (0.1 or
1.0 mg/kg) and avridine (1 or 25 mg/kg), or the immunosuppressant, cyclophosphamide (75
mg/kg). Immune responses assessed in each rat were specific antibody synthesis, delayed-
type hypersensitivity (DTH), natural killer cell (NKC) cytoxicity and production of three
immunoregulatory cytokines, interleukin 1 (IL1), interleukin 2 (IL2) and prostaglandin E 2 …